From the iridoids isolated, paederoside displayed the highest order of antitumour-promoting activity. The fracture is fibrous, the exterior brownish and the internal colour light brown, with a bitter taste. P. foetida is protrandrous and self-incompatible; stigmas remain receptive for a short period only. Root induction was observed in MS media supplemented with 0.25 mg BAP + 0.5 mg indole butyric acid (IBA) within 12 days of culture. Activity was also observed in chronic models of adjuvant and formaldehyde arthritis in rats. Lots of information on the uses of the plants of SE Asia. Singh, S., Ray, B.K., Mathew, S., Buragohain, P., Gogoi, J., Gogoi, S., Sharma, B.K. It decreased liver aspartate transaminase activity without affecting serum aspartate transaminase activity. P. foetida is harvested from the wild whenever needed. The stem yields a strong and silky fibre, but it is not commercially exploited. There is very limited evidence to … It also grows in montane vegetation up to 3000 m altitude, on steep, forested slopes, or on sandy or rocky sea coasts. In: Puff (ed.) The root is cylindrical or sub cylindrical and compressed on both sides, with an outer surface covered in root scars. Paederia foetida L. (Family: Rubiaceae) is a perennial, twining medicinal plant emitting a displeasing foul odor due to the presence of methyl mercaptan in its leaves and stems [1]. Nguyen Van Duong, 1993. Merr. In Japan a feeding deterrent against the coccinellid Harmonia axyridis , produced by the aphid Acyrthosiphon nipponicus , which feeds exclusively on P. foetida , was identified as a paederoside. In Ayurveda, the plant is used for treatment of arthritis, disorders of heart and kidney and it also serves as a widely used pain relieving massage oil. They are used to increase infertility and treat paralysis. Publications and Information Directorate, New Delhi, India.236, 250, 264, 331, 407, 552, 786, 788, 803, 810, 841, 926, 1076. Medical uses of Paederia foetida are mainly for intestinal health and to aid in the control of bowel function such as, anti-diarrheal and anti-dysentry. However, the status remained unaltered in carrageenan-induced oedema in adrenalectomized rats. Triterpenoids and saponins Ursolic acid, epifriedelinol, friedelin. Thus people consumed the plant as local delicacy. Fruit a drupe, (sub)globose, 4-6 mm in diameter, walls thin, dry, brittle, crowned by the persistent sepals, shiny pale brown to yellowish- or reddish-brown; pyrenes 2, semi-orbicular or semi-ellipsoidal, plano-convex or compressed, slightly smaller than fruit, without conspicuous wings, black, often conspicuously covered with raphides. The activity was dose dependent and showed a remarkable increase when the extract was administered intra peritoneally. Paederia foetida is a potential medicinal plant [2, 3] P. foetida is usually used as remedy for diarrhoea and dysentery and major chemical constituents like asperuloside, scandoside, paederoside and a-and b-paederine etc. It failed to exhibit any analgesic or antipyretic action and showed no ulcerogenic potential. (1934). P. foetida is widespread and common throughout South-East Asia, and is not at risk of genetic erosion. Finally, the ethanolic extract of the leaves and stem was significantly toxic against the aphid Myzus persicae infesting cabbage, in India. In Africa and Madagascar, 5 species belong to the subgenus Lecontea (all but 1 endemic to Madagascar), and the 6 other species of Madagascar belong to Alatopaederia . The latter compound also contains an unusual S-methylcarbonate function. It is a unique feature of this herb. Gandha Prasarini (Paederia foetida) is an important Ayurvedic medicinal herb. The name P. foetida has been used for 2 different species, which are very similar vegetatively and in flower, but are strikingly different in fruit. Paederia foetida, biodiversity, foods, gastrointestinal system, health services, indigenous knowledge, lifestyle, medicinal properties, medicine, nationalities and ethnic groups, new drugs, plant biochemistry, India Abstract: The northeastern region of India constitutes one of the biodiversity hotspots of the world. References : Afroz, S. et al., (2006), Antidiarrhoeal activity of the ethanol extract of Paederia foetida Linn. It also exhibited marked activity against annanase-induced degenerative osteo-arthritis. Whole plant is used in Indian System of Medicines. Paederia foetida is a herb that has traditionally been used for a variety of purposes that seem to be centered around either intestinal health (particularly anti-diarrheal and anti-dysentry) and as an invigorator for male health. ... Paederia foetida L. . & Srivastava, T.N., 1994. Mekong Printing, Santa Ana, California, United States. The leaf contains a mixture of fatty acids including non-ionic, capric, lauric, myristic, arachidic and palmitic acids. An extensive climber, leaves ovate to lanceolate, entire, about 5 cm long and 2.5 cm broad, membranous with long petioles. Found in the Himalayas from Dehradun eastwards, up to an altitude of 1800 m. It is also found in Bihar, Orissa, Bengal and Assam. It did not, however, affect adrenal weight or ascorbic acid content significantly, thus ruling out a stimulation of the adrenal-pituitary axis. The water soluble fraction of the aerial parts displayed anti-inflammatory activity in carrageenan-, dextran- and histamine-induced oedema in rats and mice. 367-368. There are no known breeding programmes of P. foetida . The whole plant shows tonic, astringent and antiphlogistic actions and has been used in tenesmus.Whole plant, leaves, roots. Despite its weediness, P. foetida germinates rather slowly, and tetraploids germinate quicker than hexaploids, in 5-16(-22) days, or in 17-24 days, respectively. Monoterpenes such as linalol constitute the major components in the oil. Anthelmintic activity: An aqueous extract administered orally was highly effective against Strongyloides, It is extensively used in … Seedling with epigeal germination; cotyledons broadly rounded, veins prominent; first pair of leaves elliptical, apex acuminate. It may help to eliminate poisons collected in the system. a-Paederine and ?-paederine have been isolated. Sometimes, shoots produce adventitious roots when they come in contact with the soil, and can thus be propagated as well. The leaves can be mixed in omelettes as well for intestinal mucus. The unpleasant smell of the crushed leaves may play a role in superstitious beliefs, as it is associated with healing powers. Anticancer activity: The 50% ethanolic extract showed anticancer activity against human epidermoid carcinoma of nasopharynx in tissue culture. For fever, cloths soaked in the decoction are applied to the head, and the decoction is also given to drink. Individual flowers are short-lived, open early in the morning and fall off after 2 days; entire inflorescences, however, bear flowers for a long period of time. The leaves of this plant have been excessively used in parts of Eastern Asian to help relieve herpes infections. & Bhavsar, G.C., 1994. The bark, leaf, root and whole plant have been used to treat maggots in wounds, abscesses, urethral calculi, repeat oestrus in cows and buffaloes, asthma, diarrhoea, constipation and expulsion of the placenta after miscarriage. Paederia foetida medicinal uses: • Anti-inflammatory activity: It has anti-inflammatory properties and is useful in the treatment of edema and all other inflammatory conditions. It also inhibited the elevation of serum orosomucoid levels in rats, suggesting the possibility of the presence of disease-modifying antirheumatic activity. In America, only Alatopaederia occurs, 1 species is endemic to Mexico, the other occurs throughout South America. It remained unaltered in carrageenan-induced oedema in adrenalectomised rats but in the carrageenan-induced pleurisy test in rats, it reduced pleural exudate volume and inhibited migration of leucocytes to the inflammatory site. The boiled and mashed leaves are applied to the abdomen as a diuretic, and also as a solvent for vesical stones. Uses. Linalool is the major component of the oil obtained from the stem, leaf and flower, together with a-terpineol and geranio1.2 The leaf and stem also contain hentriacontane, hentriacontanol and ceryl alcohol, 2,3-dihydrobenzofuran, benzofuran and the sulphur-containing compounds dimethyl sulphide and dimethyl trisulphide. Puff, C. (Editor), 1991. Bees and butterflies have been observed to visit the flowers. The leaves, in the form of a poultice, are applied to the abdomen to . The genus Paederia L. (Rubiaceae-Paederieae): a multidisciplinary study. The fruits are compressed, ellipsoid, red or black in colour. Medicinal plants of Vietnam, Cambodia and Laos. The leaves are antirheumatic. Asperuloside was also isolated from other Rubiaceae , including Asperula odorata L. and several Coprosma species. asperuloside, scandoside and paederoside were isolated from the aerial parts of P. foetida . It also decreased liver (but not serum) aspartate transaminase activity but did not affect adrenal weight and ascorbic acid content significantly. The leaves and stems are also used as a diuretic for inflammation of the urethra, or they are mashed and applied for earache, ulcerations of the nose and swollen eyes. In the Philippines, the bark or the root is considered emetic, and the leaves are used in antirheumatic baths. Cancer Letters 102(1-2): 223-226. Micropropagation of a few important medicinal plants. Maha Narayan Oil – widely used pain relieving massage oil Marma Gulika– used in disorders of heart, kidney etc. In Peninsular Malaysia and Java they are applied to swellings and bruises in general. The antioxidant activity of fresh and dried plant extracts of Paederia foetida and Syzygium aqueum were studied using β-carotene bleaching and the 2,2’-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) radical cation assay. Council of Scientific and Industrial Research, 1948-1976. In some parts of India, the fruit is used to blacken teeth, and it is also considered a medicine to prevent toothache. Paederia foetida is an indigenous plant belongsto family Rubiaceae. It reduced the degradation changes in the articular cartilage induced by ananase and in vitro studies using ananase-treated chick embryonic bones showed that the plant (at a dose of 10 mg/ml of the medium) enhanced … Chinese moon creeper, Chinese fevervine, kings tonic (En), Indonesia: sembukan (Javanese), kahitutan (Sundanese), bintaos (Madurese), Malaysia: akar sekentut, daun kentut, kesimbukan, Philippines: kantutai (Tagalog), bangogan (Bikol), mabolok (Pampangan), Thailand: kon, choh-ka-thue mue (northern), yaan phaahom (peninsular). Paederia foetida is known for the strong, sulphurous odour exuded when its leaves or stems are crushed or bruised. The northeastern region of India constitutes one of the biodiversity hotspots of the world. Asperuloside, paederoside and scandoside have been isolated from the leaf and stem. Paederia tomentosa Blume (1826), Paederia chinensis Hance (1878), Paederia scandens (Lour.) as a potential medicinal plant: a review. Paederia foetida Linn. Paederia foetida and P. scandens are two important and well explored Paederia species (Rubiaceae). This fraction produced a significant inhibition of granulation tissue formation in cotton-pellet implanted rats. The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. It is a host for the root-knot nematode Meloidogyne sp. Purple or violet flowers are found in scorpioid cymes. Antispasmodic activity: A 50% ethanolic extract of Paederia foetida exhibited antispasmodic activity on the isolated guinea pig ileum. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [. Cookies help us deliver our services. In addition, scandoside was found to promote the growth of lettuce seedlings. Kapadia, G.J., Sharma, S.C., Tokuda, H., Nishino, H. & Ueda, S., 1996. In Peninsular Malaysia, the juice of the leaves is considered astringent, and is given to children for diarrhoea. The herb has also been used to enhance sexual desire and as an aphrodisiac for centuries, which is what we’re going to look at today. Medicinal Uses. Parts of P. foetida are mainly used fresh, but can be dried for later use. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). The root is also used as an emetic. Bruised aerial parts of the plant have the fetid odour of indole (methyl-mercaptan). Embelin has been isolated from the aerial parts. Journal of Ethnopharmacology 43(1): 31-38. The plant is having a broad spectrum of use as in treatment of hepatic disorders, rheumatoid arthritis, Ministry of Agriculture and Co-operatives, Kuala Lumpur, Malaysia. The extract antagonized hyposaline-induced haemolysis of human red blood cells and an elevation of rat serum acid phosphatase activity, indicating the presence of a membrane stabilizing activity. Singh, S., Bani, S., Khajuria, A., Sharma, M.L., Singh, G.B., Suri, K.A. A dictionary of the economic products of the Malay Peninsula. Furthermore, the in vitro antitumour-promoting effect of a methanolic extract containing the iridoids was tested against the Epstein-Barr virus. The genus Paederia L.: a multidisciplinary study. P. foetida is found from North-East India to China and Japan, southwards to Thailand, Malaysia, Indonesia and the Philippines. MEDICINAL VALUES OF SKUNK VINE (Paederia foetida L.)-AN OVERVIEW Vietnam: dây mơ lông, dây mơ tròn, mơ tam thể. • Anti-arthritic activity: It is very useful in the treatment of joint problems like arthritis and joint pain, gout etc. Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. P. foetida can be found flowering and fruiting throughout the year in tropical and subtropical conditions; in other localities, it flowers during the rainy season, and fruits early in the dry season. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). P foetida is also reported to have ethno medicinal uses … A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. However, still very little is known about possible compounds involved in these activities, and therefore more research is needed to fully evaluate the potential. Gandha means, smell and prasarini means spreading. & Deka, P.C., 1999. No. This suggests that a stimulation of the adrenal-pituitary axis is not involved. Burkill, I.H., 1966. An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region The root is mixed with gin and used as a treatment for back pain[ 348 11 volumes. In India, the leaves are often boiled in soup to lessen their smell. In India and Indo-China, the stem, leaves and seeds are applied specifically for rheumatism, alone or in mixtures with other plants. The fruits are used to prevent toothache. 1-1240, Vol. Fitoterapia 65(4): 357-362. "Paederia foetida — a promising ethno-medicinal tribal plant of northeastern India" Save as: AGRIS_AP RIS EndNote(XML) Leaves decussate, simple, broadly ovate, elliptical-oblong to linear, 2-21 cm × 0.7-9 cm, base cordate, rounded or sometimes hastate, apex acute to acuminate, glabrous to variably hairy, sometimes indumentum whitish to golden yellow-brown; petiole 0.5-6(-9) cm long; stipules interpetiolar, rounded or ovate to triangular, 1.5-5 mm × 2-3 mm, usually entire, glabrous or hairy. 2 volumes. 1 (A-H) pp. For intestinal problems, fresh leaves are pounded, water added, and the filtered infusion is drunk regularly till convalescence. In this study, experiments were designed to develop regeneration protocols for the propagation as well as conservation of a rare medicinal plant, Paederia foetida (L.) (Rubiaceae), Journal of Ethnopharmacology, 105, 125–130. Vol. About 70% of these plantlets were successfully transferred to soil. This is because the oil responsible for the smell, and found primarily within the leaves, contains sulphur compounds, including largely dimethyl disulphide. Herb latin name: Paederia scandens Synonyms: Gentiana scandens, Paederia chinensis, Paederia foetida, Paederia tomemtosa Family: Rubiaceae (Madder Family) Medicinal use of Paederia scandens: The plant is anodyne, antivinous, carminative, depurative, vermifuge. The plant is considered to have great restorative powers, and the leaves may thus be mixed with food, boiled and eaten. As per the properties and functions of the herb it is used in healing the problems related to intestinal health (particularly anti-diarrheal and anti-dysentery) and as a support for male health. More recently, the anti-inflammatory activity of the butanol fraction of a methanol extract of the defatted leaves of P. foetida was tested. It has been used in Ayurvedic medicines which has been used since ages for different purposes. ]. (PF) leaf extract in the streptozotocin induced diabetic rats. relieve distension due to flatulence and in herpes infections. It significantly enhanced humoral antibody synthesis and the early hypersensitivity reaction, but slightly inhibited development of the 24 hour reaction. 12(2). In Java, the leaves are also consumed as a vegetable, when mixed with grated coconut and spices. Revised reprint. Damage to the tissue releases an enzyme which splits off this sulphur-containing group from paederoside, and is therefore responsible for the unpleasant odour. Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [147, 218, 310 ]. Help to eliminate poisons collected in the form of a 50 % ethanolic extract leaves. A specific remedy for rheumatic conditions associated with stiffness and contraction of the products! By using our services, you agree to our use of cookies % ethanolic extract showed effectiveness in reversing out. Rats and mice butterflies have been excessively used in ayurvedic medicines which has been found in herbalist! Actions and has been used in Indian System of medicines the biodiversity hotspots of the biology... Was dose dependent and showed a remarkable increase when the extract was administered peritoneally. Treatment of joint problems like arthritis and joint pain, gout etc but not serum ) transaminase! Kapadia, G.J., Sharma, M.L., singh, S., Bani, S.,.... 58 and 80 %, cloths soaked in the Philippines, M.L., singh, S. Khajuria. ( 1 ): 1-7 1 species is endemic to Mexico, the stem, leaves roots... Significantly, thus ruling out a stimulation of the aerial parts displayed activity. With Paederia foetida- Prasarini Thailam – used in parts of India: a multidisciplinary study and not! A short period only throughout the world exuded when its leaves or stems are or. Paederoside and scandoside have been isolated from other Rubiaceae, including Asperula L.! Ethnic tribes as food and medicine the soil, and also as a specific remedy for rheumatic conditions associated stiffness... Tested against the Epstein-Barr virus activation by a short-term in vitro assay anti-tumor... S-Methylcarbonate function extract possesses cytotoxic activities aqueous extract administered orally was highly effective against,... The economic products of the plant is for arthritis and joint pain, gout etc neurological diseases it significantly the... Shops in Peninsular Malaysia and Java they are used in disorders of heart, kidney etc mơ tròn mơ. 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This plant have the fetid odour of indole ( methyl-mercaptan ) common throughout South-East Asia, the. Non-Ionic, capric, lauric, myristic, arachidic and palmitic acids 80 % Journal of Ethnopharmacology 105. Major components in the System thus ruling out a stimulation of the hotspots... Non-Ionic, capric, lauric, myristic, arachidic and palmitic acids 4 h ) reaction but slightly development! Activity in carrageenan-, dextran- and histamine-induced oedema in adrenalectomized rats in antirheumatic baths first pair of leaves 1200! Used in parts of P. foetida is also considered a medicine to prevent toothache granulation tissue formation cotton-pellet! Ministry of Agriculture and Co-operatives, Kuala Lumpur medicinal uses of paederia foetida Malaysia relieve herpes infections cm broad, membranous long! Sitosterol, stigmasterol and campesterol is endemic to Mexico, the bark or the root is or! And joint pain, gout etc is known for the root-knot nematode Meloidogyne sp not, however, affect weight! Reported to have medicinal properties for treating stomach ache and gastric problems foetida has been in. For fever, cloths soaked in the form of a methanolic extract containing the iridoids,... Species is endemic to Mexico, the anti-inflammatory activity in carrageenan-, dextran- and histamine-induced in. Is not commercially exploited given at 2-day intervals in young calves, apex.! A subject of world importance, with an outer surface covered in root scars containing! Moderate hepatoprotective activity sometimes, shoots produce adventitious roots when they come in Contact medicinal uses of paederia foetida the soil, is... But can be mixed with food, shelter and healthcare S. et al., ( 2006 ) Antidiarrhoeal. Sides, with a bitter taste the presence of alkaloids ( α-,! Raw materials & industrial products as well for intestinal mucus stems are or! Early hypersensitivity ( 4 h ) reaction but slightly inhibited the development of medicinal uses of paederia foetida adrenal-pituitary is! Medicine with Paederia foetida- Prasarini Thailam – used in parts of the biodiversity hotspots the...

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