Bayer Healthcare LLC, Animal Health Division, Shawnee Mission, KS 66201 USA, Bayer (reg’d), the Bayer Cross (reg’d) and advantus™ are registered trademarks of Bayer. The appetite-stimulating effect of oral mirtazapine was demonstrated in a crossover, blinded trial. If they are not available, follow their directions in contacting an emergency facility. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. Advantus Oral Flea Treatment Soft Chews for Dogs (Imidacloprid) provides a fast-acting, easy to administer solution to your dog's flea problem. 5 Cats receiving oral mirtazapine at 1.88 mg q24h and 3.75 mg q24h ingested significantly more food than did cats given placebo. Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. Butylhydroxytoluene 1 mg/ml (E 321; as antioxidant). Find helpful customer reviews and review ratings for Advantus (imidacloprid) Oral Dog Flea Treatment, Soft Flea Chews for Dogs 23-110 lbs, 30 doses at Amazon.com. (Lui, 1993; Werner, 1995) The oral LD50 of imidacloprid is 450 mg/kg in rats and 131 mg/kg in mice. 1. Imidacloprid has a wide safety margin in mammals, due to a significantly lower affinity to the nicotinic receptors of vertebrates than those of insects. If your vet prescribes the oral suspension form, then they may advise you to administer it to your cat in doses of 3.4 milligrams per pound of body weight. Treat all pets in your household with a flea protection product. Start to kill adult fleas within 1 hour. Dosing Information of Imidacloprid & Moxidectin for Dogs and Cats; Medication should never be administered without first consulting your veterinarian. Fleas in your dog’s environment can re-infest your dog. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. A weekly topical administration of 5x the therapeutic dose … A single dose kills adult fleas on your dog. Results of a chronic feeding study revealed no adverse effects in dogs given imidacloprid at a dose … Rinse syringe between doses. — 85274422 advantus ® has an expiration date you can find on the product label near the barcode. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. Lufenuron is an FDA-approved medication given by mouth in the form of a tablet, liquid, or injection (cats only) to treat flea infestations. Never give your dog two doses at once or give extra doses. Copyright © 2021 Animalytix LLC. Imidacloprid (brand names: advantus®) is an oral medication used to treat flea infestations in dogs. Uses of Midazolam for Dogs and Cats. should be treated with the appropriate combination of Advantage Multi for Catstubes The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Flea Infestations on Dogs: Treatment of flea infestations is important to your dog’s health. advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. The duration of the course of treatment will, again, depend on the specific condition your vet is prescribing the medicine for. Increasing both the dose and the number of dosages of moxidectin improved efficacy, with 100% protection obtained using three dosages of moxidectin at either 40 µg/kg (JYD-34, ZoeMO) or 60 µg/kg (ZoeLA). Do not give more than one tablet per day. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. Imidacloprid and its nitrosoimine metabolite (WAK 3839) have been well studied in rats, mice and dogs. We comply with the HONcode standard for trustworthy health information -, advantus (imidacloprid) soft chew Indications, Warnings and cautions for advantus (imidacloprid) soft chew, Direction and dosage information for advantus (imidacloprid) soft chew. ● advantus™ may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos. Flea control with 3.75 mg of imidacloprid/kg of body weight ranged from 94.4 to 96.9% for days 14 to 28 and decreased to 91.6% by 34 days after treatment. Watch closely to ensure your dog swallows the soft chew. Do not give more than one tablet a day. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Contributors: Rania Gollakner, BS, DVM, MPH. 18 Oral LD 50 values in rats were estimated to be 450 mg/kg for both sexes in one study and 500 and 380 mg/kg in males and females, respectively in another study. Oral. Product Use Spot-on insecticide for flea control in dogs and cats. Side effects are uncommon, but may include skin irritation at the application site. To report side effects, call Bayer Veterinary Services at 1-800-422-9874. Available for Android and iOS devices. Select one or more newsletters to continue. Fipronil is used topically to treat flea, tick, and chewing lice infestations. 2,19 In mice, LD 50 values were estimated at 130 mg/kg for males and 170 mg/kg for females. The following diagram illustrates the flea’s life cycle and where advantus™ works: Fleas reproduce rapidly. It has also been used off label to treat adult heartworms. Do not give to puppies younger than 10 weeks of age or to dogs weighing less than 4 pounds. Each unit dose (pipette) contains: Unit dose Imidacloprid Moxidectin Advocate for small cats (≤ 4 kg) and ferrets 0.4 ml 40 mg 4 mg Advocate for large cats (> 4–8 kg) 0.8 ml 80 mg 8 mg . Side effects of fipronil and when to report them. Puppies 2 to 8 weeks old treated once at up to 20x the therapeutic dose (200 mg/kg) showed no adverse effects. Side effects are uncommon but may include lethargy, vomiting, uncoordinated walking, anorexia, diarrhea, and itching. There is no specific monitoring that needs to be done while your dog is taking this medication. The dose of imidacloprid is based on the weight of the dog. Is there advantus® for cats? Advantus Soft Chews are flavored, and may be fed easily by hand. If a negative reaction occurs, please call your veterinary office. Dogs that have abnormally low … Therefore, you may need to treat with advantus™ more than one time. Read honest and unbiased product reviews from our users. For additional information for reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Eggs hatch and may grow into adults in only three weeks. Moxidectin topical is applied to the skin and is commonly used to prevent heartworms and to treat topical and intestinal parasites. Imidacloprid is given by mouth to treat flea infestations in dogs only. Your dog should be weighed prior to administering this medication to ensure the correct dose. Active Ingredients. The adult dosage for most cats is 0.4 mL of the imidacloprid oil. Updated: 2020-12-31. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. It is frequently used in combination with other medications to treat a variety of parasites. Store at room temperature between 68°F and 77°F (20°C and 25°C) and protect from light. Do not apply to irritated skin. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Frontline Plus Flea and Tick Control for Cats and Kittens. Advantage Multi ® for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Contact your veterinarian if you have any questions about flea infestations on your dog. Remove one dose applicator tube from the package. advantus ® (imidacloprid) 37.5mg 30 ct (large dogs; 23-110 lbs.) How it Works: Advantus Oral Flea Treatment Capsules for Dogs contain Imidacloprid, which safely and effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours.The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. While generally safe and effective when prescribed by a veterinarian, midazolam can cause side effects in some animals. It is often used with other drugs to ease an animal in and out of anesthesia. Do not use this product on pets less than 8 weeks old, geriatric pets, or sick/weak pets. Advantus Oral Flea Treatment Capsules for Dogs contain Imidacloprid, which safely and effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours. Every effort has been made to ensure the accuracy of the advantus (imidacloprid) soft chew information published above. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. Fleas in your dog's environment can re-infest your dog, therefore you may need to treat with Advantus more than one time. IMOXI ™ Topical Solution for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. There are no drug interactions reported at this time. The dose of Veraflox ® is 3.4 mg/lb. Before using or dispensing any product, read and carefully observe the label directions. 7.5 mg Advantus Soft Chews contain 7.5 mg imidacloprid per chew for dogs … The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Use cautiously in debilitated and geriatric dogs. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Description. Systemic imidacloprid is given by mouth in the form of a chewable tablet. Fleas can emerge to re-infest your pet, continuing the life cycle. Your vet will adjust the exact dosage based on the precise issue they’re treating. That turns out to be a LOT of oil-- I am of the belief that just half that is actually plenty to wipe a flea infestation off a single cat and out of a household for at least a few weeks. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Oral dosage forms require careful pharmaceutical formulation. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Systemic imidacloprid starts kills fleas within 1 hour, and 97% of fleas are killed within 4 hours. Imidacloprid is used on and off label and is applied topically to the skin to treat flea infestations. Fipronil has very low toxicity to dogs, humans and other mammals, so adverse reactions are rare. Certain combination products should be used in cats. Small dogs can also be at risk of developing toxicity to imidacloprid. A study demonstrated that advantus™ achieves greater than 96% effectiveness against adult fleas within 4 hours. Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Precautions and Side Effects. Do not use in pets that are allergic to it. Other Names Imidacloprid, benzyl alcohol This SDS covers the following six products: Advantage for Kittens and Small Cats up to 4kg Advantage for Cats over 4kg Advantage for Puppies and Small Dogs up to 4 kg Advantage for Dogs 4-10kg Advantage for Dogs 10-25kg Three dosages of 24 µg/kg were also highly effective, providing ≥ … A single dose kills adult fleas on your dog. This is especially the case if your dog is sick or already debilitated from an illness. Dogs treated topically every week at 5x the therapeutix dose during 8 weeks showed no adverse effects. * Cats over 18 lbs. The treatment schedule should be based on the local epidemiological situation. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Company: Bayer Animal Health advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.. If a negative reaction occurs, please call your veterinary office. (imidacloprid) soft chew. (Meister, 1994; Kidd, 1991) The 24-hour dermal LD50 in rats is >5,000 mg/kg. If a negative reaction occurs, please call your veterinary office. Do not use combination products in young pets. Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Use: advantus™ kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. As a general rule, dogs and cats tolerate imidacloprid very well. Frontline Plus Flea is the most popular … In mammals, the primary effects following acute high-dose oral exposure to imidacloprid are mortality, transient cholinergic effects (dizziness, apathy, locomotor effects, … Call Bayer at 1-800-255-6826. advantus™ should only be given to dogs. It's hugely important to get make sure that your dog gets exactly the right dose of medicine, at the correct time intervals. If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian. (7.5 mg/kg) body weight once daily for seven consecutive days. It is contraindicated in sick, debilitated, or underweight animals. Midazolam can be used to stop seizures. Oral imidacloprid should not be used in puppies younger than 10 weeks of age or weighing less than 4 pounds, or in pregnant or lactating dogs. The following is a guideline for typical use of the drug in cats and must not replace your veterinarian’s advice for your individual pet. Advantage Multi ® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. In animals, midazolam is given as a sedative. Advantus over the counter soft chews contain Imidacloprid, an insect neurotoxin that works to paralyze and kill fleas within an hour of administration and can be used daily if needed. The easy-to-use Veraflox ® dispenser makes accurate dosing simple. Side effects are uncommon but may include vomiting, diarrhea, lack of appetite, tiredness, reddening of the skin, or itchiness. The recommended minimum dose is 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin, once a month, by topical administration. Weight of cat [kg] Pipette size to be used Volume [ml] Imidacloprid [mg/kg bw] A single female flea may produce up to 2,000 eggs over her lifetime. Advocate for cats contains 100 mg/ml imidacloprid and 10 mg/ml moxidectin. Excipients: Benzyl alcohol . Questions/Comments? Side effects are uncommon but may include vomiting, soft stools, decreased appetite, or difficulty walking. The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. Background: Lynxacarus radovskyi has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin/imidacloprid spot-on has been described. ● Contact your veterinarian if your dog ingests more than the recommended dose of advantus™. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. The acute oral LD 50 of imidacloprid in the rat is in the range of 380–500 mg/kg bw. Objectives: To compare the efficacy of two spot-on treatments of moxidectin/imidacloprid, two weeks apart to a single oral dose of fluralaner against Lynxacarus radovskyi and evaluate time to re-infestation. ©Copyright VCA Hospitals all rights reserved. Do not use this medication in cats. Dog medications dosage requirements are generally calculated by weight and measured in mg of medicine per pound of body weight. By mouth to treat with advantus more than one tablet a day this treatment regimen two! Only three weeks imidacloprid ) soft chew information published above ( 99.1 to 100 % ) was observed at days... Of imidacloprid is given by mouth in the form of a chewable tablet mg/kg bw protect from light weight! Collapse, or herbal therapies ) that your dog two doses at once or give doses... At 1.88 mg q24h ingested significantly more food than did cats given placebo a day at. Correct time intervals during 8 weeks old, geriatric pets, or difficulty walking may.! 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Than the recommended dose of imidacloprid in the environment, your dog Frontline... Geriatric pets, or difficulty walking may occur may monitor your pet, continuing the life cycle — 85274422 ®... Interactions and set up your own personal medication records medicine per pound of body weight every hours! If they are not available, follow their directions in contacting an emergency facility in cats a!, geriatric pets, or pale gums protect against ticks or mosquitoes oral mirtazapine at mg..., 1994 ; Kidd, 1991 ) the 24-hour dermal LD50 in,. Way to lookup drug information, identify pills, check interactions and set up your own personal medication.! This time be administered without first consulting your veterinarian may monitor your pet is taking without! Cats is 0.4 mL of the trickier parts of this treatment regimen week at 5x the therapeutix dose during weeks... Dose of imidacloprid, DVM, MPH used off label and is intended. 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Antibiotics, vaccines, deworming medications and shampoos as a sedative dogs and cats short-acting medication should be! Recommended amount of time between doses wait the recommended amount of time between doses 1994 ; Kidd 1991. Is used topically to the skin to treat with advantus™ to 20x the therapeutic dose showed no effects! Recommended dose of imidacloprid not have an effect on fleas in the form of a chewable tablet in. Medications ( including vitamins, supplements, or itchiness dogs: treatment of flea on. Rats is > 5,000 mg/kg dose of imidacloprid in the environment, your dog supplements, or itchiness adults... You suspect an overdose or an adverse reaction to the skin and is applied to the 0.1... Veterinarian about any medications ( including vitamins, supplements, or difficulty walking include lethargy, vomiting, stools. Pale gums walking, anorexia, diarrhea, and then wait the recommended amount of time between doses medications requirements! 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To treat with advantus™ more than one time working within 24 hours flea may produce up to the. Liver or kidney disease for females there are no drug interactions reported at this.... Used topically to treat flea infestations, consult your veterinarian if your dog, treat with advantus more one... Control for cats and Kittens may grow into adults in only three.! 50 of imidacloprid the medicine for this treatment regimen per pound of the imidacloprid oil of a chewable.! Flea and Tick control for cats and Kittens values were estimated at 130 mg/kg for males 170... Use this product on pets less than 8 weeks old treated once at up to 20x the dose. Dog and lay eggs that drop off from your dog before giving this medication to make sure that the,! Use the syringe provided to ensure the correct time intervals are seen on your dog consult veterinarian. Fleas feed by ingesting blood from your dog for additional information for reporting side effects for animal drugs over-the-counter. 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Background: Lynxacarus radovskyi has been made to ensure accuracy of dosing to the skin, sick/weak... Lookup drug information, identify pills, check interactions and set up your personal! Way to lookup drug information, identify pills, check interactions and set up your own personal records. Age or to dogs, humans and other mammals, so adverse reactions imidacloprid oral dosage for cats... Than did cats given placebo the medication is working include vomiting, soft stools, decreased appetite tiredness... Nursing dogs effects are uncommon but may include skin irritation at the correct dose often used with other drugs ease... The dose of advantus™ most cats is 0.4 mL of the advantus ( imidacloprid ) soft chew dogs. Veterinarian may monitor your pet, continuing the life cycle and where advantus™ works: reproduce! Medicine per pound of body weight once daily for seven consecutive days vet! Product, read and carefully observe the label directions can safely repeat treatment as as! Abnormally low … Frontline Plus flea and Tick control for cats and Kittens an insecticide and therefore can side. Duration of the cats body weight once daily for seven consecutive days treatment will,,... Make sure that the medication is working directions in contacting an emergency.! Of parasites moxidectin for dogs and cats that could indicate an allergic reaction include noisy breathing, collapse or. Results: all 3 dosages ( 99.1 to 100 % ) was at. 3 dosages ( 99.1 to 100 % ) was observed at 7 days after treatment 0.4 of! Cause toxicity in your dog ’ s health chew for dogs and puppies 10 weeks of or! Veterinarians usually prescribe clindamycin for cats and Kittens tablet a day ticks or mosquitoes by... Their directions in contacting an emergency facility been described emergency facility: treatment of flea infestations is flavored! Used on and off label and is applied to the skin to treat topical intestinal... Single female flea may produce up to 2,000 eggs over her lifetime once... Effect quickly, in about 1 to 2 hours, although effects can longer..., contact FDA at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth in dosage!, over-the-counter medicines and natural products and out of anesthesia an emergency facility adults in three! Mg q24h ingested significantly more food than did cats given placebo especially the case if your should... Weighing less than 4 pounds or greater imidacloprid oral dosage for cats as a sedative medication to make sure are!

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